We are interested in studying the presence of the immediate early gene nur77 in steroidogenic tissues and tumors. We are looking at the effects of TGF-b on the induction of the Nur77 protein in Y-1 cells and other steroidogenic tissues and tumors. We are also interested in the role of the Nur77 protein in steroidogenisis.

SELECTED PUBLICATIONS:

Mohamood, A.S., P. Gyles, K.B. Balan, V.W. Hollis, W.R. Eckberg, A. Assefa, Z. Han, J.H. Wyche and W.A. Anderson. 1997. Estrogen receptor, growth factor receptor, and protooncogene protein activities and possible signal transduction crosstalk in estrogen-dependent and independent breast cancer cell lines. J. Submicroscop. Cytol. Pathol. 29, 1-7.

Bhattacharyya, N.R., R. Ramsammy, E. Eatman, V.W. Hollis, and W.A. Anderson. 1994. Protooncogene, growth factor, growth factor receptor, and estrogen and progesterone receptor gene expression in the immature rat uterus after treatment with estrogen and tamoxifen. J. Submicroscop. Cytol. Pathol. 26, 147-162.

Simpikins, C.O., B.P. Chenet, Y-H Kang, D.L. Mazorow, D.B. Millar and V.W. Hollis,Jr. 1989. Human erythrocytes have binding sites for beta-endorphin. J. Natl.Med. Assoc. 81, 1149-1153.